The use of gene therapy to treat genetic diseases Essay

The use of gene therapy to treat genetic diseases - Essay ExampleAn item-by-item has sickle jail cubicle trait when one of the 2 copies is carrying the sickle cell beta globin gene. On the other hand, if both the copies carry sickle cell beta globin gene then the individual has sickle cell anemia and suffers from the debilitating disease. In accordance with predictable patterns of inheritance there are four possibilitiesi. An individual with linguistic rule beta globin hemoglobin genes has children with an individual possessing two copies of sickle cell gene dedicate a 100% opportunity that all their children will sustain sickle cell trait i.e. one customary gene and one sickle cell gene.ii. When two individuals with sickle cell trait have children then each of their offsprings has a 50% chance of having sickle cell trait, 25% chance of inheriting normal homozygous genes i.e. two normal copies of beta globin hemoglobin gene and 25% chance of inheriting two copies of sickle cell gene.iii. If an individual possessing normal beta globin hemoglobin genes has children with an individual having sickle cell trait then each child has a 50% chance of inheriting two copies of normal beta globin hemoglobin genes and an equal chance of having sickle cell trait.iv. In case an individual having sickle cell trait decides to have children with an individual having sickle cell anemia then each child has a 50% chance of having sickle cell trait and a 50% chance of having sickle cell anemia. (JONES 2008).Hemophilia is a recessive, X linked disease therefore, genetic segregation and dominance play an important role in the inheritance of hemophilia. The recessive mutated forms of clotting factor VIII and IX are present on the X chromosome. Therefore, the disease is more common in males because they have a single X chromosome and if it has the mutated gene then the person will have hemophilia as unlike females they do not have another(prenominal) X chromosome for compensat ion. In females, the dominant X